Within the past decade, we have seen a considerable increase in the popularity of skin care lines that claim to help protect the skin from oxidative damage and reverse existing damage.
Many of these companies, especially those sold commercially in stores, have little or no clinical scientific data to support most of their claims.
In addition, antioxidants may minimize the damage to DNA, an effect that may prevent skin cancer development.
Although there are no current studies to support a protective effect against cancer, the importance of antioxidants should be stressed as a potential preventive measure and be used as an important adjunct to sunscreen.
Abstract book http://www.nutrition.uio.no/throneholst/Abstract book.pdf
Dietary supplementation with fruit or vegetable extracts high in antioxidant capacity can decrease this vulnerability as assessed by a range of in vivo and in vitro measures.
nourished young subjects, whereas supplementation in smokers appeared to reduce oxidation of DNA bases.
This secondary hyperparathyroidism causes increased bone resorption, leading to bone loss and contributing to fractures in the elderly.
If our results may be extrapolated to longer supplementation periods (which is not sure at this time), it may be calculated that the age at which increased fracture risk becomes obvious could be shifted to higher ages by 8-10 years.
An investigation of the expression of the retinoid receptors RARs mRNA during malignant progression of mouse skin carcinogenesis has demonstrated a downregulation of these transcriptional regulators as the cells become more malignant and progress to metastatic.
comet_assay
DNA damage, antioxidant, supplem, dogs, comet assay, free radicals.
Can dietary antioxidants ameliorate DNA damage in cats and dogs?
-- certain drugs, anaesthetics -- radiation eg. free radicals O. & OH.
Ageing = free radical production + antioxidant defences Leading to accumulation of DNA damage potentially contributing to sub-optimal cellular function and the development of degenerative disorders (e.g. cancer and arthritis).
baseline 4 wk Potential to reduce DNA damage through nutrition?
What does this mean from a specific functional point of view?
No supplem ent AOX cocktail What does this mean from a specific physiological point of view?
BV_PlumBro_m_v3_Nutrition http://www.californiadriedplums.org/filestor/nutrbroc/BV_PlumBro_m_v3_Nutrition.pdf
dried plums, fruit, Antioxidants, fiber, oxidation, prunes.
After all, California's dried plums originated about 150 years ago when seedlings from France's petite prune d'Agen were grafted to the root stock of the California wild plum.
Today, California's dried plums are considered among the finest in the world and the state is the international leader in dried plum production.
The name, prunes, however, was never able to capture the essential qualities of this luscious dried fruit.
Antioxidants, both soluble and insoluble dietary fiber, vitamins and minerals --you'll find many good reasons to enjoy dried plums daily.
Oxidation is cellular damage caused by free radicals that are produced in the body as a by-product of metabolism.
cs_refrigeration
Laboratories, ppm ppm, acid buildup, oil, oxidation, antioxidants.
Laboratory Data -- Acid Number, Water, Copper and Iron were elevated in sample # 40709 and P40710.
Infrared analysis shows the antioxidants in samples P40709 and P40710 are depleted.
In addition there is large C=O (oxidation) peak present.
circOil® Analysis -- The circOil® shows P40709 and P40710 are much darker than the normal samples indicating depletion of antioxidants additives and oxidation of the oil.
Recommendation: Take appropriate maintenance actions to reduce acid buildup, i.e. drain the oil for Lab.# 40709 and P40710.
Sample weekly with circOil to monitor acid buildup.
Additional testing was performed due to the high circOil rating.
TJ_Here's to Your Health
Infections, antioxidants, websites, Disease, treatment, hydrogen peroxide.
It is your job to investigate the validity of these claims and make recommendations as to the appropriate method of treatment for these ailments.
You will do this by comparing alternative medicine's assertion of oxygen therapy to conventional medicine's belief in antioxidants.
You have already performed an experiment which will gave you "hands-on" experience with a model system, the common potato.
Your evaluation will be based on your group work and your presentation of findings at the debriefing session.
During this period, investigate the use of food grade hydrogen peroxide in oxygen therapy.
During this period, investigate the relationship between oxidative damage and antioxidants/antioxidant enzymes.
supplementsB http://ddl.uwinnipeg.ca/hhs/files/supplementsB.pdf
disease, nutrition, vitamin, cancer, supplements, health.
· Why should I take nutritional supplements?
· Over the past two decades, scientific evidence has accumulated showing an indisputable link between good nutrition and long-term health.
· Diet plays a central role in determining the risks of many birth defects, childhood illnesses, and chronic degenerative diseases.
· 30-40% of heart disease deaths are attributed to obesity and high blood cholesterol.
· Additional risk is traced to diets low in antioxidants and B vitamins.
· Not designed as optimal levels of nutrient intake.
· Compliment a healthy diet, and provide the advanced levels of essential nutrients shown to significantly reduce the risks of chronic degenerative disease.
Tocotriene_Complex
rice bran, stabilized rice, antioxidants, Tocotriene Complex, nutrients, healthy.
The rice kernel's inner layer, rice bran, contains a huge storehouse of precious but delicate super nutrients.
Among the most powerful of its naturally-occurring antioxidants are oryzanols, tocopherols, and tocotrienols.
Tocotriene Complex is a hypoallergenic, antioxidant-rich su-per-food with three amazing, highly nutritious components: stabilized rice bran, stabilized rice protein and FOS (fructooligosaccharides) made from chicory.
A favorite way to eat it is to add it to cereal as a topping or sprinkle it on warm flatbread.
2. We have combined quality stabilized rice protein and delicious, sweet-tasting FOS with our stabilized rice bran to deliver both top nutrition and a great taste without chemical sweeteners.
supplementsB http://ddl.uwinnipeg.ca/hhs/files/supplementsB.pdf
disease, nutrition, vitamin, cancer, supplements, health.
· Why should I take nutritional supplements?
· Over the past two decades, scientific evidence has accumulated showing an indisputable link between good nutrition and long-term health.
· Diet plays a central role in determining the risks of many birth defects, childhood illnesses, and chronic degenerative diseases.
· 30-40% of heart disease deaths are attributed to obesity and high blood cholesterol.
· Additional risk is traced to diets low in antioxidants and B vitamins.
· Not designed as optimal levels of nutrient intake.
· Compliment a healthy diet, and provide the advanced levels of essential nutrients shown to significantly reduce the risks of chronic degenerative disease.
Tocotriene_Complex
rice bran, stabilized rice, antioxidants, Tocotriene Complex, nutrients, healthy.
The rice kernel's inner layer, rice bran, contains a huge storehouse of precious but delicate super nutrients.
Among the most powerful of its naturally-occurring antioxidants are oryzanols, tocopherols, and tocotrienols.
Tocotriene Complex is a hypoallergenic, antioxidant-rich su-per-food with three amazing, highly nutritious components: stabilized rice bran, stabilized rice protein and FOS (fructooligosaccharides) made from chicory.
A favorite way to eat it is to add it to cereal as a topping or sprinkle it on warm flatbread.
2. We have combined quality stabilized rice protein and delicious, sweet-tasting FOS with our stabilized rice bran to deliver both top nutrition and a great taste without chemical sweeteners.
Polymerdegradation
polymer, chain, radiation, reaction, molecular, bond.
Rate at which gases and vapors permeate polymer films depends on the partial pressure gradient across the film.
The C-C bond energy is about 330 kJ/mol corresponding to a photon wavelength of 360 nm.
Radiation induced scission of a primary chemical bond is called RADIOLYSIS.
Oxidation of polymer materials involves free radical chain reactions.
For example, it is known that a hydrogen atom is less easily removed from a location such as I (secondary hydrogen atom) than from II (tertiary H atom).
The first cycle is the alkyl/alkylperoxyl chain reaction and the second involves the homolysis of hydroperoxides which feeds the chain reaction with new radicals.
CI020460
scald, storage, apples, harvest, antioxidants, temperature.
The effect of harvest date, GA, as pre-storage treatment and storage temperature (5" C for various periods) on superficial scald incidence was tested during the period 1993-94.
The internal concentration of antioxidants, a-farnesene and conjugated trienes by using peel n-Hexane extracts was determined at harvest and at the end of the storage period.
The damage on the skin of the fruit is caused by conjugated trienes produced after oxidation of a-farnesene (Huelin and Coggiola, 1970; Meigh, 1970).
Also, it has been suggested that the content of natural antioxidants (e.g. a-tokopherol) plays an important role in preventing oxidation of a-farnesene and consequently scald development (Anet, 1974; Meirand Bramlage, 1988).
july_august_2002 http://www.carlsonlabs.com/pdf/july_august_2002.pdf
vitamin, milk, foods, consumption, health, risk.
There is no doubt that eating the proper foods is important to optimal health, but in many cases you cannot obtain adequate vitamin support from foods.
For example: To obtain only 100 IU of vitamin E from food you need to consume 2 ½ cups of almonds or 6 ½ cups of sweet potatoes (two of the top sources of vitamin E).
A Canadian study was conducted on 83 infants who were enrolled within two weeks of birth and exclusively breast fed for four months by mothers whose diets were supplemented to increase DHA content of their breast milk.
Between 1970 and 1973, over five thousand men in Scotland filled out a survey of milk consumption.
1-4020-7085-3
disease, cell, molecular, protein, vivo, oxidation.
A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes.
Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.
Contents and Contributors: ROS/RNS in Cell Injury and Disease.
Upregulation of phosphoinositide 3-kinase and protein kinase B in alveolar macrophages following ozone inhalation.
Depletion of Bcl-2 by an antisense oligonucleotide induces oxidation and externalization of phosphatidylserine at early stages of apoptosis in NCI-H226 lung carcinoma cells; P.P. Koty, et al. 15.
myths
skin, vitamin-C, L-ascorbic acid, antioxidants, formulation, ingredients.
Topical Vitamin-C: L-Ascorbic Acid vs. Vitamin-C Esters L-ascorbic acid and vitamin-C esters are equally effective forms of topical vitamin-C.
If a product containing one antioxidant is good for your skin, then a product containing a cocktail of two, three or four antioxidants will be that much more effective.
When formulating combination antioxidant skin care products, the key to achieving maximum efficacy is the formulation, concentration and synergy of the ingredients being used -- not the number of antioxidants within the formulation.
Physical Sunscreens: Zinc Oxide vs. Titanium Dioxide Zinc oxide and titanium dioxide provide identical UV protection.
Walk into any drugstore, department store or dermatology office and you will find a plethora of products fortified with a combination of antioxidants, such as vitamin-C, vitamin-E, silymarin, and alpha lipoic acid.
