Irritable bowel syndrome (IBS) is a condition of chronically altered gastrointestinal function

Psychopharmacology - and Kids Child and adolescent psychiatrist Jud Staller MD, who is seeking patients for a clinical study of the metabolic and endocrine effects of antipsychotic drugs on children and adolescents, has also documented a dramatic increase in CNY's use of psychopharmacology for treating young patients. Page A2 Women who suffer from disabling, diarrhea-predominant Irritable Bowel Syndrome may be candidates for a new multicenter clinical trial led by gastroenterologist Philip Holtzapple MD. Paper bricks are plastering the walls of local pediatrician's waiting rooms and sending a clear message: pediatric patients and their parents enthusiastically support the plan to build the CNY Children's Hospital at University Hospital. SUNY Upstate's Jud Staller MD studies the long-term safety of antipsychotic drugs for children - and tracks the growing trend toward psychopharmacology for young patients. During two decades as a child and adolescent psychiatrist, Jud Staller

OA/Bowel65

Background/Aim of Study: Data on the epidemiology of bowel frequency and functional bowel disorders in the East are limited. The aims of this study were to determine the most common bowel frequency and the prevalence of functional bowel disorders in Singaporean adults. Results: The most common (59.0 + 6.5%) bowel frequency was once a day with 96.8 + 5.6% of individuals having bowel frequency between 3 times/ week and 3 times/day. Conclusions: Normal bowel frequency may be defined as bowel movements between 3 times per week and three times per day. The prevalence of irritable bowel syndrome in the general population of Singapore was low compared with those reported in the West. Keywords: bowel frequency, functional bowel disorder, irritable bowel syndrome, constipation, diarrhoea Depending on the criteria used, irritable bowel syndrome (IBS) has been reported in 17-22% of the healthy population(1-3), chronic constipation in 3-17%(3,4) and chronic diarrhoea

Nyhedsbrev_ UK 03406-102

Irritable bowel syndrome (IBS) is a condition of chronically altered gastrointestinal function characterized by abnormal motility of the large intestine, and possibly also the small in-testine, without the presence of any demonstrable organic changes. No unambiguous pathological or biological marker exists that is specifically able to diagnose irritable bowel, which must consequently be considered a syndrome. Tegaserod for the treatment of irritable bowel syndrome A review of its use in the management of irritable bowel syndrome with constipation in women. Evidence-based position state-ment on the management of irritable bowel syndrome in North America. Tegaserod for the treatment of irritable bowel syndrome Müller-Lissner SA, Fumagalli I, Bardhan KD, et al. Tegaserod, a 5-HT4 receptor partial agonist, relieves symptoms in irrita-ble bowel syndrome patients with abdominal pain, bloating and constipation. A randomised, double-blind, placebo-controlled trial of tegaserod

REF

There are no definitive and reliable biological, sociological or psychological markers of Irritable Bowel Syndrome (IBS) even though IBS patients traditionally show more psychological distress and greater prevalence in Gastroenterology Departments (G.D) than the general population. Understanding if shift-working is directly associated with IBS, or if other subtle indirect associations are present has been difficult for previous studies to achieve, when not attempting to investigate work-related factors beyond those of "occupation". The biospychosocial approach to investigating occupational associations with Gastrointestinal (G.I) disorders employed in this study will acknowledge the interactive process between individual psychosocial factors, job choice and retention, health-modifying behaviours and health awareness. By accounting for individual psychosocial factors, it will be possible to ascertain how influential occupational factors actually are in the aetiology
Measuring the frequency of functional gastrointestinal disorders in rural Crete: a need for improving primary care physicians' diagnostic skills The aim of this study was to report on the frequency of functional dyspepsia (FD), irritable bowel syndrome (IBS) and gastroenteritis within the primary care setting, to provide some information on the extent to which the recorded diagnoses in the physicians' notes fulfil existing diagnostic criteria. The two most common functional gastrointestinal disorders in the population are functi onal dyspepsia and irritable colon. Irritable bowel syndrome (IBS) is characterised by persistent or recurrent abdominal pain related to defecation or to chronic disturbance of bowel habits in the absence of demonstrable organic disease. We also included all cases with the diagnoses `diarrhoea and fever,' `diarrhoeic syndrome,' and `acute diarrhoea.' all cases that met the criteria defined by Talley (any persistent or recurrent pain or discomfort

AnnConfPR

What have dietitians, organic food and irritable bowel syndrome got in common? The three day Conference will be opened by Yvette Cooper, Parliamentary under Secretary of State for Public Health. The Majestic Hotel will be packed with eminent speakers and key opinion formers from government, industry, academia and the NHS who will discuss a wide range of current issues relating to food and health. A full programme is available on www.bda.uk.com. Members of the Press wanting more information, who want to attend all or part of the conference, or who wish to interview any speakers, please contact: Organic food is `natural' and therefore better? Dr Keith Goulding of Rothamsted Experimental Station in Hertfordshire will present the available scientific evidence on organic food and farming, which he believes questions the widely held belief that organic foods are better for you than conventionally produced foods. Dominic Dyer from the Food and Drink Federation

191 POEMs.PC

Cesarean delivery does not prevent pelvic organ prolapse Clinical Question: Are nulliparous women who un-dergo cesarean delivery less likely to develop a pelvic organ prolapse than women who deliver vaginally? SYNOPSIS A cohort of 101 nulliparous women with uncomplicat-ed singleton pregnancies was evaluated for pelvic organ prolapse according to the International Conti-nence Society staging system by comparing stage at 36 weeks' gestation to that at six weeks postpartum. Women were grouped by type of delivery for compar-ison. Clinical Question: What is an appropriate diagnostic evaluation for patients meeting the criteria for irritable bowel syndrome? SYNOPSIS A concern of patients with irritable bowel syndrome (IBS) and their physicians is when to stop looking for another diagnosis. The preva-lence (for diagnostic purposes, the pretest probability) of different diseases among patients meeting criteria for IBS was as follows: colitis/inflammatory bowel disease, 0.5% to 1.0%;

18 October 2004

Tegaserod (Zelmac®, Norvatis) was registered in Singapore in April 2002. It is a serotonin 5-HT4 receptor partial agonist indicated for the symptomatic treatment of abdominal pain and discomfort, bloating and altered bowel function relating to irritable bowel syndrome (IBS) in female patients whose main symptoms are pain/discomfort and constipation. FDA updates tegaserod label with new risk information The US Food and Drug Administration (FDA) has recently approved the amended package insert of Zelmac® to include safety information regarding diarrhoea with serious complications associated with the drug and post-marketing reports of ischaemic colitis (IC). In conjunction with FDA's announcement, the manufacturer, Norvatis, issued a letter to health professionals in the US highlighting the label changes which include the following: a) Serious consequences of diarrhoea (such as hypovolaemia, hypotension and syncope, some of which required hospitalisation for rehydration) have
Achlorhydria, acute gastritis, #252 p.89-94 Acupuncture, inflammatory disorders, #250 p.131 Acupuncture, irritable bowel syndrome, #252 p.117 Acupuncture (warm needle), post-operative bladder numbness, #251 p.58 Acupuncture-moxibustion, fibromyalgia, #247/248 p.36-7 Acupuncture-moxibustion, migraine headaches, #249 p.135 Adaptogenic effects, Rhodiola rosea, #246 p.161-3 Adaptogens, chronic fatigue syndrome, #247/248 p.66-8 Addiction, reward deficiency syndrome, #249 p.26 Adrenal hormones, #246 p.116+ Advanced glycation endproducts, autoimmune disease & inflammation, #250 p.123-4 Advanced prostate cancer, lycopene, #251 p.40 Autoimmune disease, Chinese medicine, #250 p.36-42 Autoimmune disease, diet, #250 p.123-4 Autoimmune disease, probiotics, #250 p.94-8 Autoimmune disease, psychological factors, #250 p.46+ Autoimmune disease, vitamin D deficiency, #250 p.75-6 Autoimmune thyroiditis, chronic fatigue syndrome, #250 p.26 Boswellia serrata, inflammatory bowel disease, #251

IBS GUIDELINES

IBS (Irritable Bowel Syndrome) is a chronic relapsing disorder of gastrointestinal function, the main features of which are abdominal pain associated with an altered bowel habit, in the absence of any structural pathology. A syndrome of alternating diarrhoea and constipation. IBS is one of the functional disorders of the gut, others include functional dyspepsia, functional diarrhoea or constipation without abdominal pain, abdominal bloating without a disordered bowel habit. Intestinal dysmotility: There are abnormalities of contractions in the small and large bowel in some patients. Abdominal pain associated with a disorder of bowel habit can occur in a number of illnesses. Do they want bowel cancer excluded or significant symptoms controlled, or are they presenting for some other reason? Reassuring the patient that IBS does not lead to serious bowel disorders. Irritable Bowel Syndrome Irritable Bowel Syndrome

ibsawareness2005

(AMGIF) - have joined together to proclaim April 2005 as IBS Awareness Month in Canada. IBS is a gastrointestinal disorder characterized by abdominal pain or discomfort, bloating and altered bowel movement (constipation, diarrhea or a combination of the two). "Unfortunately, people with IBS often suffer in silence because of a reluctance to discuss their bowel habits and symptoms, even with their doctors. We hope that by proclaiming April as IBS Awareness Month in Canada we can raise awareness about the symptoms of IBS - including abdominal pain, bloating and altered bowel movement - and encourage people suffering to go and talk to their doctors." (IFFGD), an American IBS patient group, declared April as IBS Awareness Month in the United States in order to heighten awareness about the syndrome, as well as emphasize the need for more research and a better understanding of IBS. ABOUT IBS Irritable bowel syndrome is a gastrointestinal disorder resulting in abdominal pain or

25-30_BIOF3301-art01

Irritable bowel syndrome (IBS) is a costly chronic health problem that affects about 10%-15% of the population and is treated with limited success in stan-dard medical care. The physiologi-cal mechanisms underlying bowel symptom improve-ment from hypnosis intervention remain poorly understood. Irritable bowel syndrome (IBS) is a chronic function-al gastrointestinal disorder that is characterized by abdominal pain and altered bowel functioning (diar-rhea, constipation, or an alternating between the two). In the first study, our physiological vari-ables of interest were bowel pain thresholds and the smooth muscle tone of the bowel wall, both of which Palsson AGA technical review on irritable bowel syndrome. Hypnotherapy in irritable bowel syndrome: A large-scale audit of a clinical service with examination of factors influencing responsiveness. Costs of care for Irritable Bowel Syndrome patients in a health maintenance organization. Changes in

IrritableBowelSyndromeUHS

Irritable bowel syndrome (IBS) is a common disorder of the intestines that leads to crampy pain, gassiness, bloating, and changes in bowel habits. Some people with IBS have constipation (difficult or infrequent bowel movements); others have diarrhea (frequent loose stools, often with an urgent need to move the bowels); and some people experience both. Sometimes the person with IBS has a crampy urge to move the bowels but cannot do so. Through the years, IBS has been called by many names: colitis, mucous colitis, spastic colon, spastic bowel, and functional bowel disease. IBS causes a great deal of discomfort and distress, but it does not cause permanent harm to the intestines and does not lead to intestinal bleeding of the bowel or to a serious disease such as cancer. If you are concerned about IBS, it is important to realize that normal bowel function varies from person to person. Normal bowel movements range from as many as three stools a day to as few as three a week.

Gastrointestinal diseases 2004_Jeppsson

What can we expect from using dietary factors in therapy of gastrointestinal diseases? difficult to standardize dietary components little available information on mechanism of action Colorectal adenoma - carcinoma Inflammatory bowel disease Irritable bowel syndrome Colorectal carcinoma COX-2 expression absent in healthy tissue, but expressed in inflammation and neoplasia Butyrate induces apoptosis in cancer cell lines and in experimental models. Supress crypt cell mitosis Increase in apoptosis n-3 polyunsaturated fatty acids Flavonoids: quercetin, myricetin, kaempferol Available for colonic fermentation: antioxidant activity, inhibition of protein kinase and cyclooxygenase activity May contribute to the protective effects of fruits and vegetables against colorectal cancer Am. Butyrate oxidation is defective in ulcerative colitis and pouchitis. In patients with distal ulcerative colitis refractory to topical steroids and 5- aminosalicylic acid (5 ASA), intrarectal

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Irritable bowel syndrome (IBS) is the most common functional bowel disorder diagnosed by primary care physicians and gastroenterologists. 2 IBS is an episodic condition that is accompanied by a wide range of symptoms, including abdominal pain and discomfort, bloating, and altered bowel function (constipation and/or diarrhea). The most common prescription therapeutic agents have the greatest impact on bowel function by either slowing down or speeding up transit times. AGA technical review on irritable bowel syndrome. The fecal microbial population in the irritable bowel syndrome. Abnormal colonic fermentation in irritable bowel syndrome. Nobaek S, Johansson M-L, Molin G, et al. Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome. Whorwell PJ, Altringer L, Morel JG, et al. Benefits associated with supplementation with an encapsulated probiotic preparation in subjects

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